{"id":2893,"date":"2018-01-31T02:20:52","date_gmt":"2018-01-31T00:20:52","guid":{"rendered":"https:\/\/academiadefarmaciadegalicia.gal\/iv-premio-de-investigacion-julian-francisco-suarez-freire-patrocinado-por-cofaga-y-cofano\/"},"modified":"2020-04-02T13:33:37","modified_gmt":"2020-04-02T11:33:37","slug":"iv-premio-de-investigacion-julian-francisco-suarez-freire-patrocinado-por-cofaga-y-cofano","status":"publish","type":"post","link":"https:\/\/academiadefarmaciadegalicia.gal\/es\/iv-premio-de-investigacion-julian-francisco-suarez-freire-patrocinado-por-cofaga-y-cofano\/","title":{"rendered":"IV Premio de investigaci\u00f3n Juli\u00e1n Francisco Su\u00e1rez Freire patrocinado por COFAGA y COFANO"},"content":{"rendered":"

Entrega de Premios 2017:<\/u><\/strong><\/span><\/h3>\n

Premio de investigaci\u00f3n de la Academia de Farmacia de Galicia: <\/u><\/strong>IV Premio Juli\u00e1n Francisco Su\u00e1rez Freire<\/strong> patrocinado por las cooperativas farmac\u00e9uticas COFAGA y COFANO<\/strong><\/span><\/p>\n

El Premio Juli\u00e1n Francisco Su\u00e1rez Freire<\/em> 2017<\/em>, patrocinado por las cooperativas farmac\u00e9uticas COFAGA y COFANO est\u00e1 dirigido a investigadores menores de 35 a\u00f1os que hayan publicado durante el a\u00f1o 2017 un trabajo original realizado en una instituci\u00f3n gallega sobre un tema relacionado con el medicamento desde sus fases tempranas de I+D hasta la cadena de distribuci\u00f3n y tiene una dotaci\u00f3n econ\u00f3mica de 3000euros.<\/p>\n

El trabajo de investigaci\u00f3n premiado, publicado en la prestigiosa revista Cell Metabolims<\/em>, abre nuevas v\u00edas para el dise\u00f1o de medicamentos en el tratamiento de la obesidad y de sus enfermedades metab\u00f3licas asociadas.<\/strong><\/p>\n

El Premio Juli\u00e1n Francisco Su\u00e1rez Freire, en su cuarta edici\u00f3n, ha sido concedido a la Dra. NOELIA MART\u00cdNEZ-S\u00c1NCHEZ<\/strong> del Departamento de Fisiolog\u00eda de la Universidad de Santiago y Centro de Investigaci\u00f3n Biom\u00e9dica en Red-Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n (CIBERobn). En el estudio, publicado en la prestigiosa revista Cell Metabolims,<\/em> han participado investigadores de 23 centros de investigaci\u00f3n nacionales e internacionales.<\/p>\n

La regulaci\u00f3n del peso corporal es un complejo proceso biol\u00f3gico que depende de la capacidad del cerebro para recibir e integrar un amplio conjunto de se\u00f1ales procedentes de todo el organismo. En este trabajo mediante estudios farmacol\u00f3gicos, fisiol\u00f3gicos y gen\u00e9ticos, se demuestra que las hormonas tiroideas inhiben la funci\u00f3n de la prote\u00edna AMPK en una poblaci\u00f3n espec\u00edfica de neuronas hipotal\u00e1micas dando lugar a la activaci\u00f3n de dos rutas moleculares que regulan la funci\u00f3n del h\u00edgado y del tejido adiposo pardo, un tipo de grasa que no almacena l\u00edpidos y que los oxida para producir calor.<\/p>\n

El mecanismo descrito abre una nueva v\u00eda para el dise\u00f1o de medicamentos en el tratamiento de la obesidad y de sus enfermedades metab\u00f3licas asociada<\/strong>s, ya que se vincula por primera vez la acci\u00f3n central de las hormonas tiroideas sobre la prote\u00edna AMPK (AMP-activated protein kinase)<\/em> con el metabolismo lip\u00eddico hep\u00e1tico y con el tejido adiposo pardo.<\/p>\n

Enlace al art\u00edculo publicado:\u00a0\u00a0http:\/\/www.cell.com\/cell-metabolism\/fulltext\/S1550-4131(17)30356-X<\/a><\/p>\n

 <\/p>\n

\"\"<\/a>\"\"<\/a> \"\"<\/a> \"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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